Yohimbine HCl Dosage for ED

Yohimbe Bark

Yohimbine (pronounced ‘yo-him-been’) is a herbal supplement extracted from the bark of a West-African evergreen tree known as Yohimbe. The botanical name of this tree is Pausinystalia Yohimbe or Corynanthe Yohimbe, it is found in several nations in West Africa. Yohimbe bark was used as traditional medicine through the ages by locals who reside in areas where the tree grows for various purposes; to increase the rate of fat loss, enhance sex drive and energy, manage erectile dysfunction, etc. Yohimbine is an alkaloid that serves as a sort of stimulant at the right dose. Chemically synthesized Yohimbine is known as Yohimbine Hydrochloride (Yohimbine HCl), a synthetic version that bears a pharmacological equivalence to the Yohimbe bark herbal extract. Yohimbe HCl is a prescription-only drug, i.e. you need a doctor’s prescription to purchase the drug.

Considering the challenge erectile dysfunction poses to a lot of men, erectile dysfunction patients are ready to use any medication as long as it works. Erectile dysfunction is a sexual health condition that defines the inability of a man to maintain a normal state of erection when sexually aroused; it is commonly called ‘ED’. Although erectile dysfunction is mostly known to affect older men (those above the age of 45), young men also suffer from ED. Age is not the only significant factor that is being linked with the occurrence of erectile dysfunction, underlying conditions including obesity, heart-related problems, hypercholesterolemia, diabetes and other physiological and psychological factors also have a significant influence on the occurrence of ED.

Yohimbine has been used as a dietary supplement for sexual stimulation and erectile dysfunction prior to the discovery of Viagra. Studies are still being conducted to consider the potential effectiveness of Yohimbine in the treatment of erectile dysfunction because it has proved effective in some ED cases and not so effective in others. The safety of Yohimbe extract is also not confirmed because the tree bark also contains other alkaloids (in smaller amounts than Yohimbine) which might have properties different from that of Yohimbine.

When to Take Yohimbe for ED

Yohimbine belongs to a class of drugs known as Alpha-2 Adrenergic Blockers; this class of drugs is used to increase secondary blood flow. Till date, there isn’t enough information to establish the fact that it is effective in the treatment of erectile dysfunction but there have been reports of Yohimbine proving effective for some patients and otherwise for others. Considering the fact that the safety of using Yohimbe bark extracts has not been specifically established and the fact that it has not been approved by the FDA, it is important that you see a doctor before using Yohimbine.

Bottle of Yohimbine HCl

Yohimbine is usually prescribed for patients who have a combination of ED and low libido since it is a stimulant and has anti-ED properties as well. Sometimes, it is used by patients as a natural supplement in a combination therapy with smaller dosages of erectile dysfunction drugs (such as Sildenafil, Vardenafil, or Tadalafil). Like most anti-ED medications, Yohimbine works by relaxing tissues in the penis and increasing blood pressure in order to generate a solid erection.

Yohimbe Erectile Dysfunction Dosage

The dosage of a drug has everything to do with its effectiveness, if you take too little, it doesn’t work, take too much (an overdose), and it could kill you, take just the right dose for you and you are all good to go. Yohimbine is an orally administered supplement, it is effective for the treatment of various conditions, it is also used as a general stimulant, and the required dosage depends on what you need it for. According to Drugs.com, the dosage of Yohimbine for ED is “5.4 mg orally 3 times a day”. Depending on what side effects you encounter, you might need to “reduce to 2.7 mg orally 3 times a day and titrate gradually up to 5.4 mg orally 3 times a day”. Dosage also varies from one patient to another and according to individual needs.

Yohimbe Dosage

Yohimbine functions as a stimulant, it enhances physical and mental alertness, and thus you shouldn’t take it when you plan to sleep or rest. You should use the drug in the morning or early afternoon when you are fully active. Yohimbine HCl can also be used on an as-needed basis by erectile dysfunction patients as long as the daily prescribed dose is not exceeded. How long does it take for Yohimbe to kick in? The effects of Yohimbine might kick in about 10-15 minutes after administration; it may take more time for some individuals to experience the effects of the drug. It has a short half-life, that is, the effects do not last for very long. The effects of Yohimbine can last for up to three hours but it doesn’t go beyond that. As helpful as you could find this information, it is important to consult your doctor before using prescription-only drugs.

Yohimbine Side Effects

Consideration must be given the side effects of a drug before it is recommended or administered. Like every other drug, Yohimbine comes with its own side effects, the intensity of these side effects can increase with dosage, and hence the drug should be taken in moderation. Side effects of Yohimbine include anxiety, irregular blood pressure and heart rate, headache, palpitations, anxiety, dizziness, visual disturbances, nausea or abdominal cramps, a rise in body temperature and sweating.


Yohimbine is a great herbal supplement, and it can be used for ED too. If you are allergic to the herbal stuff, you can get the chemically synthesized version. It is not recommended for men over the age of 65 to take Yohimbine, especially if the underlying cause of your ED is a heart-related condition. Since high doses can cause disorientation and confusion, it should never be consumed while operating a vehicle or performing hazardous activities. Check out our list of Top recommended online pharmacies if you wish to purchase an approved pharmaceutical treatment for erectile dysfunction.